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Of note, blood NAD metabolites were changed in all studied diseases, except for prostate cancer, while glutathione metabolites demonstrated alteration only in cancers (Fig

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First, regarding Aβ generation, the palmitoylation of both Amyloid Precursor Protein (APP) and its processing enzymes, including β-secretase, promotes their interaction and cleavage efficiency at the membrane (Ouyang et al., 2024)