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4 Enterovirus infection as an environmental trigger of T1D There have been reports associating T1D with lower microbial diversity, diet, low vitamin D exposure, and exposure to toxins and chemical compounds in food or water ( Figures 1 , 2 ) ( Enterovirus infection has been associated with T1D for decades ( Picornaviridae family, which includes coxsackieviruses, polioviruses, and encephalomyocarditis virus

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