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Boosting Thioredoxin-1 Protects Against Acetaminophen-Induced Cardiotoxicity Molecular Cell Biology Unit, Division of Biochemistry, Faculty of Science, Tanta University, Tanta 31527, Egypt Molecular Carcinogenesis Laboratory, Department of Zoology, Faculty of Science, Tanta University, Tanta 31527, Egypt Department of Histology and Cell Biology, Faculty of Medicine, Alexandria University, Alexandria, Egypt Abstract Background: Although overdose-induced acute hepatic failure following acetaminophen (APAP) administration is well documented, clinical studies have also reported myocardial infarction, cardiac dysfunction, arrhythmias, pericarditis, and cardiac myocyte necrosis in APAP poisoning